Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867010 | 0.88 | ALDH1A1 (0.39) | HRH3ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL9866678 | 0.87 | HRH3 (0.44) | HRH3ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL9873107 | 0.87 | HRH3 (0.38) | HRH3ALDH1A1KMT2AGAAMEN1 | |
| Iodide SCHEMBL10445022 | 0.87 | ALDH1A1 (0.39) | HRH3ALDH1A1KMT2AGAAMEN1 | |
| Iodide SCHEMBL10445057 | 0.87 | HRH3 (0.43) | HRH3ALDH1A1KMT2AGAAMEN1 | |
| Iodide SCHEMBL10445026 | 0.86 | HRH3 (0.37) | HRH3ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL9602724 | 0.82 | ALDH1A1 (0.46) | HRH3ALDH1A1KMT2AGAAMEN1 | |
| Fumaric Acid SCHEMBL9603083 | 0.81 | MCHR1 (0.39) | HRH3ALDH1A1KMT2AGAAMEN1 | |
| Fumaric Acid SCHEMBL9603089 | 0.81 | MCHR1 (0.39) | HRH3ALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL9602093 | 0.79 | HRH3 (0.39) | HRH3ALDH1A1KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |