Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601550 | 0.86 | HRH3 (0.40) | HRH3MCHR1DRD2 | |
| SCHEMBL9601997 | 0.85 | HRH3 (0.39) | HRH3DRD2 | |
| SCHEMBL9602165 | 0.84 | HRH3 (0.41) | HRH3MCHR1DRD2 | |
| SCHEMBL9602826 | 0.83 | ATM (0.48) | — | |
| SCHEMBL9602367 | 0.82 | ATM (0.47) | DRD2 | |
| SCHEMBL9602957 | 0.81 | PTGS1 (0.42) | — | |
| SCHEMBL9602428 | 0.81 | HRH3 (0.41) | HRH3MCHR1DRD2 | |
| SCHEMBL9602093 | 0.80 | HRH3 (0.39) | HRH3DRD2 | |
| Fumaric Acid SCHEMBL9866109 | 0.79 | HRH3 (0.37) | HRH3 | |
| SCHEMBL9602470 | 0.79 | KDM4E (0.51) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |