Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602165 | 0.93 | HRH3 (0.41) | HRH3ALDH1A1GAAKMT2ADRD2 | |
| SCHEMBL9602911 | 0.91 | HRH3 (0.38) | HRH3ALDH1A1GAAKMT2ADRD2 | |
| SCHEMBL9602470 | 0.87 | KDM4E (0.51) | ALDH1A1KMT2ADRD2 | |
| SCHEMBL9602093 | 0.84 | HRH3 (0.39) | HRH3ALDH1A1GAAKMT2ADRD2 | |
| SCHEMBL9601997 | 0.84 | HRH3 (0.39) | HRH3ALDH1A1GAAKMT2ADRD2 | |
| SCHEMBL9601550 | 0.84 | HRH3 (0.40) | HRH3ALDH1A1GAAKMT2ADRD2 | |
| SCHEMBL9873107 | 0.83 | HRH3 (0.38) | HRH3ALDH1A1GAAKMT2ADRD2 | |
| Iodide SCHEMBL10445026 | 0.82 | HRH3 (0.37) | HRH3ALDH1A1GAAKMT2ADRD2 | |
| SCHEMBL9602367 | 0.81 | ATM (0.47) | KMT2ADRD2 | |
| SCHEMBL9867239 | 0.81 | HRH3 (0.39) | HRH3DRD2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351435-B1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |