Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.39 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | NPC1 | O15118 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.37 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.37 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867325 | 1.00 | RAB9A (0.39) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL8216589 | 0.81 | MAPT (0.49) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL8216588 | 0.81 | MAPT (0.49) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL107988 | 0.77 | MAPT (0.61) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL29596363 | 0.77 | MAPT (0.61) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL107987 | 0.77 | MAPT (0.61) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL5720475 | 0.77 | MAPT (0.56) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL5720474 | 0.77 | MAPT (0.56) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL14174536 | 0.76 | RAB9A (0.47) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL9009285 | 0.75 | RAB9A (0.54) | RAB9AMAPTNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015769-A | Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination | L'OREAL (FR) | 1991-05-14 | — | — | US | disclosed |
| US-4904276-A | Nitroaminophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate nitroaminobenzenes and their use in dyeing keratinous fibres | L'OREAL (FR) | 1990-02-27 | — | — | US | disclosed |
| US-4749379-A | HAIR DYES | L'OREAL (FR) | 1988-06-07 | — | — | US | disclosed |
| US-4740622-A | 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols | L'OREAL (FR) | 1988-04-26 | — | — | US | disclosed |