Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337415 | 1.00 | SIRT2 (0.53) | SIRT2SIRT5TACR1HDAC8F2 | |
| SCHEMBL9865766 | 0.89 | SIRT2 (0.49) | SIRT2SIRT5TACR1HDAC8ITGB3 | |
| SCHEMBL9335609 | 0.89 | SIRT2 (0.49) | SIRT2SIRT5TACR1HDAC8ITGB3 | |
| SCHEMBL9335795 | 0.87 | CTSL (0.51) | SIRT2SIRT5TACR1HDAC8ITGB3 | |
| SCHEMBL9865730 | 0.87 | CTSL (0.51) | SIRT2SIRT5TACR1HDAC8ITGB3 | |
| SCHEMBL9335637 | 0.83 | KMT2A (0.48) | SIRT2HDAC8SIRT1SIRT3 | |
| SCHEMBL8443041 | 0.82 | CTSL (0.52) | TACR1 | |
| SCHEMBL9335708 | 0.82 | NR1H4 (0.49) | KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL9865584 | 0.77 | NAMPT (0.60) | KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL9339382 | 0.76 | SIRT2 (0.57) | SIRT2SIRT5HDAC8SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |