Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335795 | 1.00 | CTSL (0.51) | CTSLCTSBCTSSCTSKHDAC8 | |
| SCHEMBL9867447 | 0.87 | SIRT2 (0.53) | HDAC8SIRT2TACR1SIRT5ITGB3 | |
| SCHEMBL9337415 | 0.87 | SIRT2 (0.53) | HDAC8SIRT2TACR1SIRT5ITGB3 | |
| SCHEMBL9335609 | 0.87 | SIRT2 (0.49) | CTSLCTSBCTSSCTSKHDAC8 | |
| SCHEMBL9865766 | 0.87 | SIRT2 (0.49) | CTSLCTSBCTSSCTSKHDAC8 | |
| SCHEMBL9866336 | 0.83 | LMNA (0.54) | — | |
| SCHEMBL4163972 | 0.81 | TACR1 (0.64) | CTSLCTSBCTSSCTSKHDAC8 | |
| SCHEMBL8443308 | 0.81 | CTSS (0.60) | CTSLCTSBCTSSCTSKHDAC8 | |
| SCHEMBL8830310 | 0.81 | CTSS (0.60) | CTSLCTSBCTSSCTSKHDAC8 | |
| SCHEMBL9864867 | 0.81 | NR1H4 (0.51) | KDM1AMAOARCOR1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |