Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867822 | 0.83 | MAPT (0.55) | ALDH1A1MAPTTP53HSD17B10HPGD | |
| SCHEMBL9877197 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTTP53HSD17B10HPGD | |
| SCHEMBL9866517 | 0.75 | CA2 (0.51) | ALDH1A1MAPTTP53HSD17B10HPGD | |
| SCHEMBL9866657 | 0.74 | NPC1 (0.46) | ALDH1A1MAPTTP53HSD17B10HPGD | |
| SCHEMBL9866528 | 0.74 | CYP19A1 (0.41) | ALDH1A1MAPTTP53HSD17B10HPGD | |
| SCHEMBL9867210 | 0.74 | ADORA3 (0.58) | ALDH1A1TP53L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL9875069 | 0.74 | CYP19A1 (0.41) | ALDH1A1MAPTTP53HSD17B10HPGD | |
| SCHEMBL21887689 | 0.73 | NQO1 (0.64) | ALDH1A1MAPTTP53HSD17B10HPGD | |
| SCHEMBL24217511 | 0.72 | ALDH1A1 (0.67) | ALDH1A1MAPTTP53HSD17B10HPGD | |
| SCHEMBL9868361 | 0.71 | MKNK1 (0.41) | KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985450-A | TREATMENT OF GLAUCOMA | AVENTIS PHARMACEUTICALS INC. | 1991-01-15 | — | — | US | claimed |