SCHEMBL986793

SCHEMBL986793

O=C(O)c1cc(-n2c3ccccc3c3ccccc32)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.57
L3MBTL1 Q9Y468 3/20 0.57
ATM Q13315 1/20 0.57
ALDH1A1 P00352 5/20 0.53
NR4A1 P22736 2/20 0.52
NPSR1 Q6W5P4 2/20 0.47
POLB P06746 2/20 0.47
FOLH1 Q04609 1/20 0.47
HPGD P15428 2/20 0.46
PTPN1 P18031 1/20 0.46
P2RX4 Q99571 1/20 0.44
NSD2 O96028 1/20 0.44
G6PD P11413 1/20 0.44
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
RORC P51449 1/20 0.43
MAPT P10636 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
LMNA P02545 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133459 0.86 KDM4E (0.54) KDM4EL3MBTL1ATMALDH1A1NPSR1
SCHEMBL21760733 0.85 FOLH1 (0.62) KDM4EL3MBTL1ATMALDH1A1NR4A1
SCHEMBL11330837 0.85 L3MBTL1 (0.66) KDM4EL3MBTL1ATMALDH1A1NPSR1
SCHEMBL30295439 0.85 L3MBTL1 (0.66) KDM4EL3MBTL1ATMALDH1A1NPSR1
SCHEMBL23534547 0.83 KDM4E (0.71) KDM4EL3MBTL1ATMALDH1A1NPSR1
SCHEMBL13018710 0.83 KDM4E (0.65) KDM4EL3MBTL1ATMALDH1A1NR4A1
SCHEMBL29362582 0.83 KDM4E (0.71) KDM4EL3MBTL1ATMALDH1A1NPSR1
SCHEMBL64816 0.83 KDM4E (0.71) KDM4EL3MBTL1ATMALDH1A1NPSR1
SCHEMBL14732447 0.83 L3MBTL1 (0.50) KDM4EL3MBTL1ATMALDH1A1NPSR1
SCHEMBL21760735 0.82 KDM4E (0.69) KDM4EL3MBTL1ATMALDH1A1NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9859505-B2 Charge-transporting molecular glass mixtures, luminescent molecular glass mixtures, or combinations thereof or organic light emitting diodes and other organic electronics and photonics applications MOLECULAR GLASSES, INC. (US) 2018-01-02 US disclosed
US-20150053894-A1 Charge-transporting Molecular Glass Mixtures, Luminescent Molecular Glass Mixtures, or Combinations Thereof for Organic Light Emitting Diodes and other Organic Electronics and Photonics Applications Molaire Consulting 2015-02-26 US disclosed
US-20150053894-A1 Charge-transporting Molecular Glass Mixtures, Luminescent Molecular Glass Mixtures, or Combinations Thereof for Organic Light Emitting Diodes and other Organic Electronics and Photonics Applications Molaire Consulting 2015-02-26 US disclosed
CN-101952251-B Carbazole-based hole transport and /or electron blocking materials and /or host polymer materials GEORGIA TECH RES INST 2014-11-26 CN disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
WO-2011000873-A1 PHOSPHORESCENT PLATINUM COMPLEXES, THEIR MONOMERS AND COPOLYMERS, AND USES IN ORGANIC ELECTRONIC DEVICES GEORGIA TECH RESEARCH CORPORATION (US) 2011-01-06 WO disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
EP-2234969-A2 CARBAZOLE-BASED HOLE TRANSPORT AND /OR ELECTRON BLOCKING MATERIALS AND /OR HOST POLYMER MATERIALS Georgia Tech Research Corporation (US) 2010-10-06 EP disclosed
WO-2009080799-A2 CARBAZOLE-BASED HOLE TRANSPORT AND /OR ELECTRON BLOCKING MATERIALS AND /OR HOST POLYMER MATERIALS GEORGIA TECH RESEARCH CORPORATION (US) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials OCIAD1, HPD, OXA1L KDM4E 4260/4885L3MBTL1 1007/4885ATM 4224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.