Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NAMPT | P43490 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27519540 | 0.85 | ALDH1A1 (0.82) | ALDH1A1NAMPTKMT2AGAAPTPN7 | |
| SCHEMBL10731132 | 0.82 | TOP2A (0.52) | ALDH1A1NAMPTKMT2AGAARAB9A | |
| SCHEMBL14476963 | 0.81 | BCHE (0.61) | ALDH1A1NAMPTKMT2AGAARAB9A | |
| SCHEMBL9937346 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2APTPN7RAB9AKDM4E | |
| SCHEMBL12989329 | 0.80 | KMT2A (0.64) | ALDH1A1NAMPTKMT2AMDM2RAB9A | |
| SCHEMBL23303452 | 0.79 | NAAA (0.57) | ALDH1A1KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL6915485 | 0.79 | ALDH1A1 (0.60) | ALDH1A1NAMPTKMT2AGAAPTPN7 | |
| SCHEMBL9868290 | 0.79 | BCHE (0.62) | NAMPTKMT2AMDM2RAB9AKEAP1 | |
| SCHEMBL1883394 | 0.77 | PIK3CG (0.54) | ALDH1A1KDM4ELMNAPPID | |
| SCHEMBL11310806 | 0.77 | NAMPT (0.65) | ALDH1A1NAMPTKMT2AMDM2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997667-A | Pyridinyl compounds of N-carbamoyl-N-thiocarbamoyl- or N-amidino-glycine or beta-alanine useful as sweetening agents | UNIVERSITE CLAUDE BERNARD (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0321369-A1 | Heterocyclic sweeteners derived from N-carbamoyl-, N-thiocarbamoyl or N-amidino-glycine or beta-alanine | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1989-06-21 | — | — | EP | disclosed |