Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826155 | 0.84 | RORC (0.42) | RORCMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9867381 | 0.83 | MAPK14 (0.40) | RORCMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL11827159 | 0.77 | RORC (0.39) | RORCMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9868320 | 0.75 | HCAR2 (0.42) | RORCMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL171117 | 0.71 | KMT2A (0.48) | MEN1KMT2AALDH1A1TSHRHCAR2 | |
| SCHEMBL11834179 | 0.70 | RORC (0.38) | RORCMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL249404 | 0.70 | KMT2A (0.55) | MEN1KMT2AALDH1A1TSHRCYP3A4 | |
| SCHEMBL20320620 | 0.69 | HCAR2 (0.50) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL15193549 | 0.68 | HCAR2 (0.36) | RORCALDH1A1HCAR2CNR2SMN1; SMN2 | |
| SCHEMBL19228450 | 0.68 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017601-A | Anti-ulcer 5-(2-substituted ethenyl)-3(2H)-furanones | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| US-5010102-A | Anti-ulcer 5-(2-substituted ethenyl)-3(2H)-furanones | AMERICAN HOME PRODUCTS CORP. (US) | 1991-04-23 | — | — | US | disclosed |
| US-5001126-A | Anti-ulcer 5-(2-substituted ethenyl)-3(2H)-furanones | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| US-4966905-A | Anti-ulcer 5-(2-substituted ethenyl)-3-(2H)-furanones | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |