Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752911 | 0.91 | ALDH1A1 (0.57) | ALDH1A1KDM4EPKMKMT2AGAA | |
| SCHEMBL9867866 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KDM4EPKMKMT2AGAA | |
| SCHEMBL10655034 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EPKMKMT2AGAA | |
| SCHEMBL7878088 | 0.84 | TSHR (0.66) | ALDH1A1KDM4EPKMKMT2AGAA | |
| SCHEMBL30639225 | 0.84 | TSHR (0.66) | ALDH1A1KDM4EPKMKMT2AGAA | |
| SCHEMBL13739731 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2ATSHRHSD17B10 | |
| SCHEMBL9867870 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4EPKMKMT2AGAA | |
| SCHEMBL7950698 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2AGAATSHR | |
| SCHEMBL23931478 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EPKMKMT2AGAA | |
| SCHEMBL1920160 | 0.81 | MAPT (0.62) | ALDH1A1KDM4EPKMKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017584-A | Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas | STERLING DRUG INC. (US) | 1991-05-21 | — | — | US | disclosed |