Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | SRC | P12931 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 3/20 | 0.49 |
| ▸ | GABRD | O14764 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865508 | 0.87 | ALDH1A1 (0.58) | ALDH1A1KDM4ESRCEGFRHPGD | |
| SCHEMBL16110173 | 0.87 | KDM4E (0.58) | ALDH1A1KDM4ESRCEGFRHPGD | |
| SCHEMBL16110166 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL27765520 | 0.84 | KDM4E (0.61) | ALDH1A1KDM4EHPGDGABRPGABRD | |
| SCHEMBL7878088 | 0.82 | TSHR (0.66) | ALDH1A1KDM4EHSD17B10NPC1ALOX15 | |
| SCHEMBL30639225 | 0.82 | TSHR (0.66) | ALDH1A1KDM4EHSD17B10NPC1ALOX15 | |
| SCHEMBL14577313 | 0.82 | PABPC1 (0.59) | ALDH1A1KDM4ESRCEGFRHPGD | |
| SCHEMBL9868002 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10PABPC1 | |
| SCHEMBL9867870 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL23931478 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10NPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248772-B1 | HYPOTENSIVE AGENTS; ANTIARRHYTHMIA AGENTS; ANTIDIABETIC AGENTS; ANTIPROLIFERATIVE AGENTS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |