Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | C1R | P00736 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252128 | 0.80 | MAPT (0.68) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL9869172 | 0.79 | MAPT (0.47) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL9867617 | 0.78 | MAPT (0.61) | KDM4EALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL7258572 | 0.76 | SMN1; SMN2 (0.64) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL11643803 | 0.76 | RAB9A (0.49) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL4600240 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL13522986 | 0.75 | NPC1 (0.69) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL11645613 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL9646773 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL220575 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1MAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038396-A | ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1977-07-26 | — | — | US | claimed |
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |