Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | C1R | P00736 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867554 | 0.80 | NPC1 (0.50) | MAPTKMT2AMEN1C1RALDH1A1 | |
| SCHEMBL9868046 | 0.79 | KDM4E (0.59) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL9867347 | 0.78 | KDM4E (0.61) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL3043863 | 0.77 | NPC1 (0.61) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL2252128 | 0.73 | MAPT (0.68) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL9867803 | 0.70 | MAPT (0.56) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL28335514 | 0.70 | RAB9A (0.69) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL9869312 | 0.70 | MAPT (0.56) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL9868637 | 0.69 | SMN1; SMN2 (0.45) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3043855 | 0.69 | MAPT (0.61) | MAPTKMT2AMEN1F2C1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |