Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 7/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400064 | 0.83 | KIF11 (0.43) | KIF11SCN9ASCN5AGSK3BMAT2A | |
| SCHEMBL9869210 | 0.75 | KIF11 (0.41) | KIF11ALDH1A1KDM4ESCN9ASCN5A | |
| SCHEMBL16729581 | 0.73 | KIF11 (0.51) | KIF11ALDH1A1KDM4ESCN9ASCN5A | |
| SCHEMBL13806219 | 0.72 | KIF11 (0.50) | KIF11ALDH1A1KDM4ESCN9ASCN5A | |
| SCHEMBL18580527 | 0.72 | KIF11 (0.50) | KIF11ALDH1A1KDM4ESCN9ASCN5A | |
| SCHEMBL11391902 | 0.71 | HTR1D (0.40) | KIF11ALDH1A1KDM4ESCN9A | |
| SCHEMBL15723828 | 0.70 | KIF11 (0.47) | KIF11ALDH1A1KDM4ESCN9ASCN5A | |
| SCHEMBL30337231 | 0.70 | JUN (0.39) | KIF11SCN9ASCN5AGSK3BMAT2A | |
| SCHEMBL28987576 | 0.70 | JUN (0.39) | KIF11SCN9ASCN5AGSK3BMAT2A | |
| SCHEMBL27856537 | 0.70 | KIF11 (0.44) | KIF11ALDH1A1KDM4ESCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002724-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-03-07 | — | — | WO | disclosed |