Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 5/20 | 0.35 |
| ▸ | PNMT | P11086 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868222 | 0.78 | ALDH1A1 (0.40) | BRD4PARP1PNMTL3MBTL1SMN1; SMN2 | |
| SCHEMBL9867437 | 0.77 | PARP1 (0.45) | BRD4PARP1TDP1 | |
| SCHEMBL9822735 | 0.76 | PARP1 (0.44) | BRD4PARP1PNMTTDP1 | |
| SCHEMBL10805966 | 0.66 | DRD2 (0.40) | — | |
| SCHEMBL10805978 | 0.66 | POLR1A (0.37) | BRD4PARP1 | |
| SCHEMBL10810657 | 0.64 | PARP1 (0.42) | PARP1PNMT | |
| SCHEMBL16651796 | 0.64 | BRD4 (0.51) | BRD4PARP1 | |
| SCHEMBL9822840 | 0.62 | PARP1 (0.46) | BRD4PARP1TDP1 | |
| SCHEMBL10814991 | 0.61 | BRD4 (0.48) | BRD4PARP1TDP1 | |
| SCHEMBL10805809 | 0.60 | PARP1 (0.47) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |