Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868485 | 0.85 | NPC1 (0.46) | NPC1RAB9AALDH1A1CYP2C9HPGD | |
| SCHEMBL31267556 | 0.83 | ALB (0.41) | CA1CA2NPC1RAB9AALDH1A1 | |
| SCHEMBL9868355 | 0.81 | MYC (0.46) | CA1CA2NPC1RAB9AHSD17B10 | |
| SCHEMBL10449414 | 0.79 | NPC1 (0.41) | ACLYNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1263202 | 0.75 | NPC1 (0.52) | NPC1RAB9AALDH1A1CYP2C9HPGD | |
| SCHEMBL1263224 | 0.73 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1264027 | 0.73 | RAB9A (0.49) | NPC1RAB9AALDH1A1CYP2C9HPGD | |
| SCHEMBL1264313 | 0.73 | NPC1 (0.49) | NPC1RAB9AALDH1A1CYP2C9HPGD | |
| SCHEMBL1263207 | 0.72 | ALDH1A1 (0.38) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6860430 | 0.72 | NPC1 (0.43) | NPC1RAB9AALDH1A1CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071995-A | Excellent ultraviolet absorbability for polyesters and polyamides; high thermal stability | KURARAY CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0363839-A1 | 2-hydroxyphenylbenzotriazol compounds and the use thereof | KURARAY CO., LTD. (JP) | 1990-04-18 | — | — | EP | disclosed |