Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868323 | 0.86 | MAPT (0.57) | RAB9APOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL4555454 | 0.82 | NPC1 (0.74) | RAB9APOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL9867876 | 0.80 | NPC1 (0.41) | RAB9APOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL18025316 | 0.78 | NPC1 (0.69) | RAB9APOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL9869428 | 0.75 | MAPT (0.48) | RAB9APOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL22092691 | 0.74 | NPC1 (0.68) | RAB9APOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL10220064 | 0.74 | NPC1 (0.68) | RAB9APOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL1708566 | 0.72 | MAPT (0.57) | RAB9APOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL881870 | 0.72 | EPHX2 (0.60) | RAB9APOLBMAPTNPC1PTPN7 | |
| SCHEMBL20335072 | 0.72 | ITGB3 (0.63) | RAB9APOLBNPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997667-A | Pyridinyl compounds of N-carbamoyl-N-thiocarbamoyl- or N-amidino-glycine or beta-alanine useful as sweetening agents | UNIVERSITE CLAUDE BERNARD (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0321369-A1 | Heterocyclic sweeteners derived from N-carbamoyl-, N-thiocarbamoyl or N-amidino-glycine or beta-alanine | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1989-06-21 | — | — | EP | disclosed |