Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868323 | 0.86 | MAPT (0.57) | MAPTNPC1RAB9APOLBADORA3 | |
| SCHEMBL4555454 | 0.75 | NPC1 (0.74) | MAPTNPC1RAB9APOLBENPP2 | |
| SCHEMBL9868414 | 0.75 | RAB9A (0.54) | MAPTNPC1RAB9APOLBADORA3 | |
| SCHEMBL4021787 | 0.74 | ADORA3 (0.68) | MAPTADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL1708566 | 0.72 | MAPT (0.57) | MAPTNPC1RAB9APOLBADORA3 | |
| SCHEMBL11787774 | 0.72 | ABAT (0.62) | POLBSMN1; SMN2ABATKMT2ATP53 | |
| SCHEMBL25840795 | 0.71 | ALDH1A1 (0.62) | MAPTNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL23328671 | 0.68 | EPHX2 (0.54) | NPC1RAB9APOLBALDH1A1KMT2A | |
| SCHEMBL22092691 | 0.68 | NPC1 (0.68) | MAPTNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL10522147 | 0.68 | SAE1 (0.50) | MAPTRAB9APOLBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997667-A | Pyridinyl compounds of N-carbamoyl-N-thiocarbamoyl- or N-amidino-glycine or beta-alanine useful as sweetening agents | UNIVERSITE CLAUDE BERNARD (FR) | 1991-03-05 | — | — | US | disclosed |