Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 3/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869428 | 0.86 | MAPT (0.48) | MAPTPOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL9868414 | 0.86 | RAB9A (0.54) | MAPTPOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL4555454 | 0.84 | NPC1 (0.74) | MAPTPOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL18025316 | 0.80 | NPC1 (0.69) | MAPTPOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL10220064 | 0.76 | NPC1 (0.68) | MAPTPOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL22092691 | 0.76 | NPC1 (0.68) | MAPTPOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL4021787 | 0.76 | ADORA3 (0.68) | MAPTKDM4EADORA3ADORA2AADORA2B | |
| SCHEMBL1708566 | 0.74 | MAPT (0.57) | MAPTPOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL881870 | 0.74 | EPHX2 (0.60) | MAPTPOLBRAB9ANPC1ADORA3 | |
| SCHEMBL17898130 | 0.73 | NPC1 (0.74) | MAPTPOLBRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997667-A | Pyridinyl compounds of N-carbamoyl-N-thiocarbamoyl- or N-amidino-glycine or beta-alanine useful as sweetening agents | UNIVERSITE CLAUDE BERNARD (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0321369-A1 | Heterocyclic sweeteners derived from N-carbamoyl-, N-thiocarbamoyl or N-amidino-glycine or beta-alanine | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1989-06-21 | — | — | EP | disclosed |