Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23505785 | 0.77 | NOTUM (0.49) | NOTUMHTR3APDE4A | |
| SCHEMBL30451991 | 0.74 | NOTUM (0.38) | NOTUMHTR3APDE4A | |
| SCHEMBL7332352 | 0.74 | NOTUM (0.38) | NOTUMHTR3APDE4A | |
| SCHEMBL24252953 | 0.74 | NOTUM (0.38) | NOTUMHTR3APDE4A | |
| SCHEMBL13534195 | 0.74 | NOTUM (0.38) | NOTUMHTR3AMAP3K14PDE4A | |
| SCHEMBL14411960 | 0.74 | NOTUM (0.38) | NOTUMHTR3APDE4A | |
| SCHEMBL18768204 | 0.73 | NOTUM (0.38) | NOTUMHTR3A | |
| SCHEMBL9868550 | 0.73 | ERN1 (0.40) | NOTUMHTR3APDE4A | |
| SCHEMBL97779 | 0.72 | PARP1 (0.41) | — | |
| SCHEMBL9868892 | 0.72 | HTR3A (0.43) | NOTUMHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |