Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335337 | 0.87 | HTR3A (0.43) | HTR3APARP1NOTUM | |
| Hydrochloric Acid SCHEMBL11514098 | 0.86 | HTR3A (0.43) | HTR3APARP1NOTUM | |
| SCHEMBL7324153 | 0.83 | HTR3A (0.43) | HTR3APARP1NOTUM | |
| SCHEMBL8366432 | 0.82 | HTR3A (0.43) | HTR3APARP1 | |
| SCHEMBL30094449 | 0.77 | HTR3A (0.51) | HTR3APARP1 | |
| SCHEMBL4387990 | 0.77 | HTR3A (0.51) | HTR3APARP1 | |
| SCHEMBL23505785 | 0.75 | NOTUM (0.49) | HTR3ANOTUM | |
| SCHEMBL219830 | 0.75 | HTR3A (0.50) | HTR3APARP1 | |
| SCHEMBL11262018 | 0.75 | TDP1 (0.39) | HTR3A | |
| SCHEMBL24252953 | 0.73 | NOTUM (0.38) | HTR3ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | disclosed |