Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868584 | 0.93 | DRD2 (0.49) | DRD2ADRA2BADRA2CDRD3HTR2B | |
| SCHEMBL9866760 | 0.84 | DRD2 (0.52) | DRD2ADRA2BADRA2CDRD3HTR2B | |
| SCHEMBL11366374 | 0.79 | DRD2 (0.60) | DRD2ADRA2BADRA2CDRD3HTR2B | |
| Hydrochloric Acid SCHEMBL11258188 | 0.78 | DRD2 (0.59) | DRD2ADRA2BADRA2CDRD3HTR2B | |
| SCHEMBL11265100 | 0.77 | DRD2 (0.61) | DRD2ADRA2BADRA2CDRD3HTR2B | |
| SCHEMBL10810631 | 0.77 | CA2 (0.60) | DRD2DRD3LMNAADRA2ATSHR | |
| SCHEMBL9868987 | 0.77 | DRD2 (0.51) | DRD2ADRA2BADRA2CDRD3HTR2B | |
| Hydrochloric Acid SCHEMBL11259196 | 0.77 | DRD2 (0.60) | DRD2ADRA2BADRA2CDRD3HTR2B | |
| SCHEMBL9869736 | 0.76 | DRD2 (0.45) | DRD2ADRA2BADRA2CDRD3HTR2B | |
| SCHEMBL10424729 | 0.76 | DRD2 (0.59) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1062144-A | The preparation method of benzodihydropyran carboxamide derivatives | DELAGRANGE LAB (FR) | 1992-06-24 | — | — | CN | disclosed |
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |
| CN-87100978-A | Dihydrobenzofuran-and chroman-carboxamide derivatives, processes for their preparation and their use as neuroleptics | — | 1987-09-16 | — | — | CN | disclosed |