Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9866605 | 0.99 | DRD2 (0.44) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL9866760 | 0.91 | DRD2 (0.52) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL9868584 | 0.83 | DRD2 (0.49) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL9822683 | 0.76 | DRD2 (0.51) | DRD2ADRA2BADRA2CDRD3HTR2B | |
| SCHEMBL27431865 | 0.76 | DRD2 (0.41) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL9868838 | 0.76 | DRD2 (0.56) | DRD2LMNAADRA2AALOX15TSHR | |
| Hydrochloric Acid SCHEMBL9868756 | 0.76 | DRD2 (0.51) | DRD2ADRA2BADRA2CDRD3HTR2B | |
| SCHEMBL9823019 | 0.75 | DRD2 (0.48) | DRD2 | |
| SCHEMBL9867269 | 0.74 | APP (0.34) | TSHR | |
| SCHEMBL10561594 | 0.74 | DRD2 (0.68) | DRD2LMNAADRA2AALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |