SCHEMBL9868944

SCHEMBL9868944

Cc1nc2cnccc2n1-c1ccc(CSc2ccccc2C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.42
PTPRG P23470 1/20 0.42
TP53 P04637 2/20 0.41
RAB9A P51151 2/20 0.41
MAPT P10636 1/20 0.41
RECQL P46063 1/20 0.40
PRNP P04156 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9526942 0.89 KMT2A (0.47) MEN1KMT2ATP53MAPT
SCHEMBL9523956 0.89 KMT2A (0.45) MEN1KMT2ATP53
SCHEMBL9868989 0.86 MEN1 (0.42) MEN1KMT2AHSD17B10
SCHEMBL9868911 0.83 DRD1 (0.40)
SCHEMBL9337098 0.80 SGMS2 (0.43) HSD17B10
SCHEMBL9332789 0.77 KLKB1 (0.51) MEN1KMT2A
SCHEMBL9525557 0.77 MAPK1 (0.51) MEN1KMT2A
SCHEMBL9332773 0.76 MYC (0.50) HSD17B10RECQL
SCHEMBL9527192 0.76 TBXAS1 (0.48) MEN1KMT2A
SCHEMBL7505146 0.75 HSD17B10 (0.59) MEN1KMT2AHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991017162-A1 IMIDAZOPYRIDINE PAF ANTAGONISTS PFIZER LIMITED (GB) 1991-11-14 WO disclosed