Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.65 |
| ▸ | HTR1A | P08908 | 3/20 | 0.65 |
| ▸ | HTR2A | P28223 | 3/20 | 0.65 |
| ▸ | HTR2C | P28335 | 3/20 | 0.65 |
| ▸ | HTR2B | P41595 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | HTR7 | P34969 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182273 | 0.89 | NPSR1 (0.63) | NPSR1NFKB1HTR1AHTR2AHTR2C | |
| SCHEMBL20182261 | 0.89 | NPSR1 (0.63) | NPSR1NFKB1HTR1AHTR2AHTR2C | |
| SCHEMBL27964771 | 0.87 | NPSR1 (0.60) | NPSR1NFKB1HTR1AHTR2AHTR2C | |
| SCHEMBL23501891 | 0.87 | NPSR1 (0.60) | NPSR1NFKB1HTR1AHTR2AHTR2C | |
| SCHEMBL23501892 | 0.87 | NPSR1 (0.60) | NPSR1NFKB1HTR1AHTR2AHTR2C | |
| SCHEMBL19252917 | 0.86 | NPSR1 (0.63) | NPSR1NFKB1HTR1AHTR2AHTR2C | |
| SCHEMBL3043368 | 0.86 | NPSR1 (0.63) | NPSR1NFKB1HTR1AHTR2AHTR2C | |
| SCHEMBL6338422 | 0.86 | NPSR1 (0.70) | NPSR1NFKB1HTR1AHTR2AHTR2C | |
| SCHEMBL23501887 | 0.86 | BLM (0.59) | NPSR1NFKB1HTR1AHTR2AHTR2C | |
| SCHEMBL11486815 | 0.86 | NPSR1 (0.59) | NPSR1NFKB1HTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234186-B1 | USE OF OLIGOPEPTIDS FOR THE TREATMENT OF CEREBRAL DISORDERS | Fresenius AG (DE) | 1991-11-06 | — | — | EP | disclosed |
| EP-0234186-A1 | Use of oligopeptids for the treatment of cerebral disorders | Fresenius AG (DE) | 1987-09-02 | — | — | EP | disclosed |