Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | HTR1A | P08908 | 2/20 | 0.63 |
| ▸ | HTR2A | P28223 | 2/20 | 0.63 |
| ▸ | HTR2C | P28335 | 2/20 | 0.63 |
| ▸ | HTR2B | P41595 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | HTR7 | P34969 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182261 | 1.00 | NPSR1 (0.63) | NPSR1NFKB1ALDH1A1LMNATSHR | |
| SCHEMBL9868965 | 0.89 | NPSR1 (0.65) | NPSR1NFKB1ALDH1A1LMNATSHR | |
| SCHEMBL27964771 | 0.88 | NPSR1 (0.60) | NPSR1NFKB1ALDH1A1LMNATSHR | |
| SCHEMBL23501892 | 0.88 | NPSR1 (0.60) | NPSR1NFKB1ALDH1A1LMNATSHR | |
| SCHEMBL23501891 | 0.88 | NPSR1 (0.60) | NPSR1NFKB1ALDH1A1LMNATSHR | |
| SCHEMBL3043368 | 0.88 | NPSR1 (0.63) | NPSR1NFKB1ALDH1A1LMNATSHR | |
| SCHEMBL19252917 | 0.88 | NPSR1 (0.63) | NPSR1NFKB1ALDH1A1LMNATSHR | |
| SCHEMBL23501887 | 0.87 | BLM (0.59) | NPSR1NFKB1ALDH1A1LMNATSHR | |
| SCHEMBL11486815 | 0.87 | NPSR1 (0.59) | NPSR1NFKB1ALDH1A1LMNATSHR | |
| SCHEMBL23501885 | 0.87 | BLM (0.59) | NPSR1NFKB1ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570606-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2026-03-10 | — | — | US | disclosed |
| EP-3541431-B1 | MYELOPEROXIDASE IMAGING AGENTS | MASSACHUSETTS GEN HOSPITAL (US) | 2024-04-17 | — | — | EP | disclosed |
| CN-110177581-B | Myeloperoxidase imaging agents | 通用医疗公司 | 2023-01-03 | — | — | CN | disclosed |
| US-20220340524-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2022-10-27 | — | — | US | disclosed |
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2019-10-17 | — | — | US | disclosed |
| WO-2018094005-A1 | MYELOPEROXIDASE IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220340524-A1 | Myeloperoxidase Imaging Agents | MPO, CAT, EPX | NPSR1 2259/4885NFKB1 2299/4885ALDH1A1 113/4885 |
| US-12570606-B2 | Myeloperoxidase imaging agents | MPO, CBR1, NOX1 | NPSR1 530/4885NFKB1 3167/4885ALDH1A1 49/4885 |
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | MPO, CAT, EPX | NPSR1 1268/4885NFKB1 2599/4885ALDH1A1 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.