Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869226 | 1.00 | PTPN11 (0.41) | PTPN11PPARGNR5A1PLA2G4BTP53 | |
| SCHEMBL9498253 | 1.00 | PTPN11 (0.41) | PTPN11PPARGNR5A1PLA2G4BTP53 | |
| SCHEMBL9870378 | 1.00 | PTPN11 (0.41) | PTPN11PPARGNR5A1PLA2G4BTP53 | |
| SCHEMBL9870627 | 1.00 | PTPN11 (0.41) | PTPN11PPARGNR5A1PLA2G4BTP53 | |
| SCHEMBL9499324 | 0.99 | LTA4H (0.40) | PTPN11PPARGNR5A1PLA2G4BTP53 | |
| SCHEMBL9498712 | 0.95 | NPC1 (0.40) | PTPN11PLA2G4BTSHRNPC1MAPT | |
| SCHEMBL9500576 | 0.91 | ALDH1A1 (0.39) | TSHRNFKB1NFKB2RELANPC1 | |
| SCHEMBL9498391 | 0.86 | LMNA (0.37) | TP53TSHRNPC1POLBMAPT | |
| SCHEMBL9498386 | 0.85 | KDM4E (0.43) | PTPN11PPARGNR5A1PLA2G4BTP53 | |
| SCHEMBL9500276 | 0.85 | KDM4E (0.43) | PTPN11PPARGNR5A1PLA2G4BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |