Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170814 | 0.89 | TSHR (0.38) | FDPSTSHRADH1BADH1AADH7 | |
| SCHEMBL6022680 | 0.88 | ALDH1A1 (0.32) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL11403169 | 0.88 | ALDH1A1 (0.32) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL7735780 | 0.84 | TSHR (0.42) | FDPSTSHRADH1BADH1AADH7 | |
| SCHEMBL11021919 | 0.83 | FDPS (0.32) | FDPS | |
| SCHEMBL20873221 | 0.83 | FDPS (0.32) | FDPS | |
| SCHEMBL3896366 | 0.79 | TSHR (0.42) | FDPSTSHRADH1BADH1AADH7 | |
| SCHEMBL4598455 | 0.79 | TSHR (0.54) | ALDH1A1TSHRADH1BADH1AADH7 | |
| SCHEMBL540916 | 0.79 | FDPS (0.30) | FDPS | |
| SCHEMBL8015188 | 0.79 | TSHR (0.35) | FDPSTSHRADH1BADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010161-A | Of poly (phenylenebisalkylene) poly (phenylamine) with aldehyde, regenerated under hydrolysis, for use in moisture curable polyurethanes | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-04-23 | — | — | US | disclosed |
| EP-0375318-A2 | Polyaldimine derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-06-27 | — | — | EP | disclosed |