Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870267 | 0.83 | KDM4E (0.40) | POLBTDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL920438 | 0.83 | S1PR4 (0.46) | POLBTDP1KDM5AKDM5BTSHR | |
| SCHEMBL921607 | 0.81 | GABRP (0.42) | POLBTDP1KDM5AKDM5BALDH1A1 | |
| SCHEMBL27926185 | 0.81 | POLB (0.40) | POLBTDP1KDM5AKDM5BALDH1A1 | |
| SCHEMBL2160590 | 0.81 | HCAR2 (0.36) | POLBTDP1KDM5AKDM5BALDH1A1 | |
| SCHEMBL1046356 | 0.81 | KMO (0.46) | TDP1ALDH1A1KDM4ETSHRHCAR2 | |
| SCHEMBL24834805 | 0.80 | GABRP (0.47) | POLBTDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL9869424 | 0.79 | KCNH2 (0.54) | ALDH1A1KDM4EMAPTCYP3A4TSHR | |
| SCHEMBL9814931 | 0.77 | KDM4E (0.50) | POLBTDP1KDM5AKDM5BALDH1A1 | |
| SCHEMBL22102940 | 0.75 | PDE10A (0.35) | KDM4EHCAR2KMOPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997947-A | Forming 6-substituted pyridine-2,3-dicarboxylic esters followed by reacting with aminoalkanecarboxylic acid amide; herbicides, plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0296109-A2 | Derivatives of 2-(imidazolin-2-yl)nicotinic acid | CIBA-GEIGY AG (CH) | 1988-12-21 | — | — | EP | disclosed |