Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9646353 | 0.85 | SIGMAR1 (0.58) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9646857 | 0.82 | LTA4H (0.51) | KDM4EALDH1A1TDP1GAALTA4H | |
| Hydrochloric Acid SCHEMBL9647699 | 0.82 | HRH3 (0.57) | KDM4EALDH1A1TDP1LTA4HLMNA | |
| Hydrochloric Acid SCHEMBL9647708 | 0.82 | HRH3 (0.57) | KDM4EALDH1A1TDP1LTA4HLMNA | |
| Hydrochloric Acid SCHEMBL9645004 | 0.80 | SIGMAR1 (0.69) | KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL9646875 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1TDP1GAALTA4H | |
| Hydrochloric Acid SCHEMBL9644953 | 0.79 | SIGMAR1 (0.52) | KDM4EALDH1A1LMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL9646922 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1TDP1GAALTA4H | |
| Hydrochloric Acid SCHEMBL9647738 | 0.79 | SIGMAR1 (0.55) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL9644965 | 0.79 | FFAR4 (0.43) | KDM4EALDH1A1GAALTA4HTEAD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051424-A | Substituted aromatic compounds having an action on the central nervous system | AKZO N.V. (NL) | 1991-09-24 | — | — | US | disclosed |