Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9646922 | 0.99 | KDM4E (0.44) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9646353 | 0.82 | SIGMAR1 (0.58) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL9869377 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9647732 | 0.80 | HRH3 (0.41) | LTA4HHRH3LMNAMAPK1RAB9A | |
| SCHEMBL9646872 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9646917 | 0.79 | ALDH1A1 (0.44) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9646857 | 0.78 | LTA4H (0.51) | KDM4EALDH1A1TDP1LTA4HSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9645004 | 0.78 | SIGMAR1 (0.69) | KDM4EALDH1A1SIGMAR1HRH3DRD2 | |
| Hydrochloric Acid SCHEMBL9644953 | 0.77 | SIGMAR1 (0.52) | KDM4EALDH1A1MEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL9647738 | 0.77 | SIGMAR1 (0.55) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365064-B1 | SUBSTITUTED AROMATIC COMPOUNDS HAVING AN ACTION ON THE CENTRAL NERVOUS SYSTEM | AKZO N.V. (NL) | 1992-10-21 | — | — | EP | disclosed |
| US-5051424-A | Substituted aromatic compounds having an action on the central nervous system | AKZO N.V. (NL) | 1991-09-24 | — | — | US | disclosed |
| EP-0365064-A1 | Substituted aromatic compounds having an action on the central nervous system | AKZO N.V. (NL) | 1990-04-25 | — | — | EP | disclosed |