Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PLEC | Q15149 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404359 | 0.77 | CTSG (0.37) | MAPTALDH1A1TSHRCYP2A6SMN1; SMN2 | |
| SCHEMBL1509344 | 0.73 | MAPT (0.56) | MAPTGAAKDM4EALDH1A1TSHR | |
| SCHEMBL28481670 | 0.72 | TRPA1 (0.41) | MAPTKDM4EALDH1A1TSHRCYP2A6 | |
| SCHEMBL2088114 | 0.72 | CA2 (0.44) | MAPTALDH1A1CYP2A6CYP1A2CYP2D6 | |
| SCHEMBL2092710 | 0.72 | CYP2A6 (0.33) | MAPTCYP2A6 | |
| SCHEMBL2091686 | 0.72 | MRGPRX1 (0.40) | MAPTGAAKDM4EALDH1A1TSHR | |
| SCHEMBL13950989 | 0.72 | CD44 (0.41) | MAPTGAAKDM4EALDH1A1TSHR | |
| SCHEMBL2092548 | 0.72 | CYP2A6 (0.41) | MAPTGAAKDM4EALDH1A1TSHR | |
| SCHEMBL17139919 | 0.72 | MEN1 (0.36) | MAPTGAAALDH1A1CYP2A6L3MBTL1 | |
| SCHEMBL4426300 | 0.71 | CYP2A6 (0.46) | CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071986-A | For pressure or heat sensitive recording materials | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| US-5037980-A | Anxiolytic agents, hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| US-5004813-A | Produce intense, lightfast colors for pressure or heat sensitive recording materials | CIBA-GEIGY CORPORATION (US) | 1991-04-02 | — | — | US | disclosed |
| US-4876357-A | FOR PRESSURE AND HEAT SENSITIVE ELEMENTS | CIBA-GEIGY CORPORATION (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0266310-A1 | Chromogenic phthalides and azaphthalides | CIBA-GEIGY AG (CH) | 1988-05-04 | — | — | EP | disclosed |