Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 6/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869500 | 0.72 | CHRNB2 (0.42) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9843058 | 0.71 | CHRNB2 (0.40) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9869505 | 0.70 | TBXAS1 (0.44) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL6943288 | 0.69 | TBXAS1 (0.42) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL3023967 | 0.67 | CHRNB2 (0.55) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL3023965 | 0.67 | CHRNB2 (0.55) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9843049 | 0.67 | TBXAS1 (0.47) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9843054 | 0.67 | TBXAS1 (0.47) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9733100 | 0.67 | TBXAS1 (0.41) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| Bicarbonate SCHEMBL9520380 | 0.66 | CHRNB2 (0.62) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025025-A | Cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |