Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869895 | 0.88 | TRPA1 (0.40) | TRPA1TSHRTDP1L3MBTL1MAPT | |
| SCHEMBL9870868 | 0.87 | TRPA1 (0.40) | TRPA1TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9868962 | 0.85 | ACSL1 (0.39) | TSHRMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7189428 | 0.82 | MAOA (0.36) | TRPA1TSHRTDP1L3MBTL1MAPT | |
| SCHEMBL9806586 | 0.81 | ACSL1 (0.36) | TSHRMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9778579 | 0.81 | ACSL1 (0.36) | TSHRMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9849388 | 0.80 | TDP1 (0.39) | TSHRTDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL135629 | 0.79 | BID (0.43) | MAPTPPARGPPARA | |
| SCHEMBL9849817 | 0.77 | P2RX4 (0.37) | TSHRTDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL1386991 | 0.77 | MAOA (0.36) | TSHRTDP1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026492-A | Synergistic; improved wear resistance in internal combustion engines | EXXON RESEARCH & ENGINEERING COMPANY (US) | 1991-06-25 | — | — | US | disclosed |