Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306153 | 0.86 | INSR (0.69) | INSRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL1306156 | 0.86 | INSR (0.69) | INSRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL31314986 | 0.84 | INSR (0.65) | INSRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL1506734 | 0.84 | INSR (0.65) | INSRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL6556231 | 0.84 | INSR (0.67) | INSRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL8390778 | 0.80 | INSR (1.00) | INSRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL8390776 | 0.80 | INSR (1.00) | INSRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL13505630 | 0.80 | INSR (0.54) | INSRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL7221823 | 0.77 | MAPT (0.64) | INSRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL24046417 | 0.77 | INSR (0.73) | INSRMAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310014-A2 | Chromogene substrate | BEHRINGWERKE Aktiengesellschaft (DE) | 1989-04-05 | — | — | EP | claimed |
| US-5077200-A | Detection of hydrolyzing enzymes | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |
| EP-0310014-A2 | Chromogene substrate | BEHRINGWERKE Aktiengesellschaft (DE) | 1989-04-05 | — | — | EP | disclosed |