Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 4/20 | 0.67 |
| ▸ | APP | P05067 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306156 | 0.86 | INSR (0.69) | INSRAPPMAPTKMT2ARAB9A | |
| SCHEMBL1306153 | 0.86 | INSR (0.69) | INSRAPPMAPTKMT2ARAB9A | |
| SCHEMBL1506734 | 0.84 | INSR (0.65) | INSRMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL31314986 | 0.84 | INSR (0.65) | INSRMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL9869708 | 0.84 | INSR (0.67) | INSRAPPMAPTKMT2ARAB9A | |
| SCHEMBL8390778 | 0.80 | INSR (1.00) | INSRAPPMAPTKMT2ARAB9A | |
| SCHEMBL8390776 | 0.80 | INSR (1.00) | INSRAPPMAPTKMT2ARAB9A | |
| SCHEMBL8767772 | 0.77 | INSR (0.69) | INSRAPPMMP9MMP8MAPT | |
| SCHEMBL25486485 | 0.77 | SMN1; SMN2 (0.50) | INSRAPPMAPTKMT2ARAB9A | |
| SCHEMBL9308820 | 0.77 | INSR (0.73) | INSRAPPMAPTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489144-A1 | Water-soluble polymeric dye | DSM IP Assets B.V. (NL) | 2004-12-22 | — | — | EP | disclosed |