Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478651 | 0.85 | MAPK1 (0.54) | ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL1043694 | 0.85 | ALOX15 (0.51) | ALOX15ALDH1A1HSD17B10HDAC3HDAC4 | |
| SCHEMBL490908 | 0.84 | TDP1 (0.50) | ALOX15HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11106829 | 0.84 | ALOX15 (0.54) | ALOX15HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3541681 | 0.82 | MEN1 (0.49) | ALDH1A1KMT2ACNR1CNR2GAA | |
| SCHEMBL11465373 | 0.82 | ALOX15 (0.49) | ALOX15ALDH1A1HSD17B10HDAC3HDAC4 | |
| SCHEMBL19116237 | 0.82 | ALOX15 (0.49) | ALOX15ALDH1A1HSD17B10HDAC3HDAC4 | |
| SCHEMBL19926010 | 0.82 | MMP8 (0.51) | ALOX15ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL9475991 | 0.82 | ALOX15 (0.49) | ALOX15ALDH1A1HSD17B10HDAC3HDAC4 | |
| SCHEMBL6787347 | 0.82 | ALOX15 (0.49) | ALOX15ALDH1A1HSD17B10HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999361-A | Cardiovascular disorders, blood vessel relaxants | BOEHRINGER MANNHEIM GMBH (DE) | 1991-03-12 | — | — | US | disclosed |