SCHEMBL490908

SCHEMBL490908

CCOC(=O)C(C)c1ccc(OC)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
ALOX15 P16050 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GPR88 Q9GZN0 1/20 0.48
KMT2A Q03164 5/20 0.48
MEN1 O00255 4/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
PPARG P37231 1/20 0.48
GLA P06280 1/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28402553 0.86 FFAR1 (0.57) TDP1L3MBTL1KMT2AGLAPTGS2
SCHEMBL31619540 0.85 TDP1 (0.71) TDP1L3MBTL1MAPTPTGS2PTGS1
SCHEMBL3280876 0.85 TDP1 (0.71) TDP1L3MBTL1MAPTPTGS2PTGS1
SCHEMBL506523 0.85 TDP1 (0.71) TDP1L3MBTL1MAPTPTGS2PTGS1
SCHEMBL9869760 0.84 KLK7 (0.52) ALOX15KMT2AGLAHDAC3HDAC4
SCHEMBL1043694 0.84 ALOX15 (0.51) ALOX15L3MBTL1KMT2AMEN1MAPT
SCHEMBL4149744 0.83 SMN1; SMN2 (0.49) TDP1L3MBTL1GPR88KMT2AMEN1
SCHEMBL4007061 0.83 MEN1 (0.54) TDP1L3MBTL1GPR88KMT2AMEN1
SCHEMBL3279844 0.83 KMT2A (0.47) TDP1KMT2AMEN1PTGS2TSHR
1,4-Dimethoxybenzene SCHEMBL27707743 0.83 KMT2A (0.50) TDP1ALOX15L3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398089-B2 Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand NANJING CHENGZHI CLEAN ENERGY CO. LTD. (CN) 2025-08-26 US disclosed
US-20220298097-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY USING COMBINED CATALYST OF ARYL BIDENTATE PHOSPHINE LIGAND NANJING CHENGZHI CLEAN ENERGY CO. LTD. (CN) 2022-09-22 US disclosed
CN-111087306-B Method for preparing organic carboxylic ester by aryl bidentate phosphine ligand combined catalysis 南京诚志清洁能源有限公司 2021-08-03 CN disclosed
WO-2021129138-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY MEANS OF COMBINATORIAL CATALYSIS WITH ARYL BIDENTATE PHOSPHINE LIGAND 南京诚志清洁能源有限公司 2021-07-01 WO disclosed
WO-2021129138-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY MEANS OF COMBINATORIAL CATALYSIS WITH ARYL BIDENTATE PHOSPHINE LIGAND 南京诚志清洁能源有限公司 2021-07-01 WO disclosed
CN-111087306-A Method for preparing organic carboxylic ester by aryl bidentate phosphine ligand combined catalysis 南京诚志清洁能源有限公司 2020-05-01 CN disclosed
US-8268293-B2 Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives MERCK PATENT GMBH (DE) 2012-09-18 US disclosed
US-8106233-B2 Applying di-2-ethylhexyl 4-hydroxy-3,5-dimethoxy-benzylmalonate; protective action against UV rays, oxidative stress on body cells, counters skin ageing MERCK PATENT GMBH (DE) 2012-01-31 US disclosed
US-20080171004-A1 Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives MERCK PATENT GMBH (DE) 2008-07-17 US disclosed
US-20080152603-A1 Antioxidants SUSONITY Commercial GmbH (DE) 2008-06-26 US disclosed
CN-101203278-A Ultraviolet protection MERCK PATENT GMBH (DE) 2008-06-18 CN disclosed
EP-0120304-A2 Substituted 4,10-dihydro-10-oxothieno benzoxepins and intermediates thereof, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1984-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080152603-A1 Antioxidants GPX4, GPX1, CAT TDP1 1049/4885ALOX15 156/4885L3MBTL1 4336/4885
US-20080171004-A1 Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives HPD, HAAO, UGT1A6 TDP1 2793/4885ALOX15 1546/4885L3MBTL1 3978/4885
US-20220298097-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY USING COMBINED CATALYST OF ARYL BIDENTATE PHOSPHINE LIGAND POF1B, ADH1C, OSBP TDP1 4211/4885ALOX15 274/4885L3MBTL1 3331/4885
US-12398089-B2 Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand POF1B, ADH1C, OSBP TDP1 4211/4885ALOX15 274/4885L3MBTL1 3331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.