Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363688 | 0.88 | GPR35 (0.47) | MAPK1ALDH1A1LMNAGAAHTT | |
| SCHEMBL10362934 | 0.84 | HTT (0.41) | TSHRMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL9869407 | 0.82 | ADRA2A (0.44) | MAPK1ALDH1A1LMNAGAAHTT | |
| SCHEMBL10363088 | 0.79 | ERN1 (0.41) | MAPK1ALDH1A1GAAHTTHPGD | |
| SCHEMBL10363095 | 0.78 | APP (0.55) | MAPK1ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL10364667 | 0.77 | HTT (0.36) | TSHRMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL10363111 | 0.77 | NPSR1 (0.36) | TSHRMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL11461967 | 0.77 | TSHR (0.43) | TSHRMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL11638792 | 0.77 | MAPT (0.47) | TSHRMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL10363663 | 0.77 | MAPK1 (0.47) | TSHRMAPK1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992471-A | Fluorinated carboxanilide | LILLY INDUSTRIES LIMITED (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0201193-B1 | CARBOXANILIDES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-10-24 | — | — | EP | disclosed |
| EP-0238351-A2 | Molluscicides | LILLY INDUSTRIES LIMITED (GB) | 1987-09-23 | — | — | EP | disclosed |
| EP-0201193-A2 | Carboxanilides | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-11-12 | — | — | EP | disclosed |