Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363688 | 0.92 | GPR35 (0.47) | ADRA2AADRA2BADRA2CALDH1A1GPR35 | |
| SCHEMBL10363559 | 0.87 | VCAM1 (0.44) | ADRA2AADRA2BADRA2CALDH1A1GPR35 | |
| SCHEMBL10383485 | 0.82 | MAPT (0.56) | ADRA2AALDH1A1RAB9AMAPTKMT2A | |
| SCHEMBL9869841 | 0.82 | TSHR (0.37) | ALDH1A1MAPTKMT2AMAPK1MEN1 | |
| SCHEMBL9871280 | 0.82 | MAPT (0.56) | ADRA2AALDH1A1RAB9AMAPTKMT2A | |
| SCHEMBL10362934 | 0.81 | HTT (0.41) | ALDH1A1RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL10363025 | 0.80 | HTT (0.44) | MAPTKMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL9868953 | 0.79 | PDK1 (0.56) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL10363610 | 0.78 | HTT (0.39) | ALDH1A1GPR35RAB9AMAPTKMT2A | |
| SCHEMBL10363792 | 0.78 | HTT (0.39) | ADRA2AADRA2BADRA2CRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992471-A | Fluorinated carboxanilide | LILLY INDUSTRIES LIMITED (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0201193-B1 | CARBOXANILIDES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-10-24 | — | — | EP | disclosed |
| EP-0238351-A2 | Molluscicides | LILLY INDUSTRIES LIMITED (GB) | 1987-09-23 | — | — | EP | disclosed |
| EP-0201193-A2 | Carboxanilides | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-11-12 | — | — | EP | disclosed |