Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CLK2 | P49760 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 11/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 11/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870331 | 0.92 | KDM4E (0.70) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL10914440 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9869882 | 0.87 | TOP2A (0.61) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9870932 | 0.85 | KDM4E (0.69) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL28942279 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL29690151 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9869220 | 0.84 | HPGD (0.62) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL8433684 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL312664 | 0.84 | ALDH1A1 (0.84) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9869688 | 0.83 | TOP1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | claimed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | claimed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | claimed |
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |