Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871775 | 0.84 | MAPK1 (0.59) | RIPK1MAPK1 | |
| SCHEMBL9871057 | 0.77 | RIPK1 (0.49) | RIPK1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL122207 | 0.75 | MAPK1 (0.76) | RIPK1POLBMAPK1 | |
| SCHEMBL10756366 | 0.74 | RIPK1 (0.61) | RIPK1POLBMAPK1MEN1KMT2A | |
| SCHEMBL10812821 | 0.74 | MAPK1 (0.74) | RIPK1POLBMAPK1 | |
| SCHEMBL10761439 | 0.74 | RIPK1 (0.60) | RIPK1MAPK1PTGS2 | |
| SCHEMBL12770967 | 0.73 | POLB (0.64) | POLBMAPK1NPC1GAARAB9A | |
| Potassium Ion SCHEMBL2691671 | 0.72 | RIPK1 (0.59) | RIPK1MAPK1PTGS2 | |
| SCHEMBL10812826 | 0.72 | RIPK1 (0.59) | RIPK1MAPK1PTGS2 | |
| SCHEMBL9870858 | 0.72 | POLB (0.65) | POLBKMT2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059599-A | Anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1991-10-22 | — | — | US | disclosed |