Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 18/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10812826 | 0.97 | RIPK1 (0.59) | RIPK1MAPK1PTGS2 | |
| Potassium Ion SCHEMBL7190441 | 0.86 | RIPK1 (0.51) | RIPK1MAPK1 | |
| SCHEMBL122207 | 0.86 | MAPK1 (0.76) | RIPK1MAPK1 | |
| SCHEMBL10756366 | 0.85 | RIPK1 (0.61) | RIPK1MAPK1PTGS2 | |
| SCHEMBL10761439 | 0.84 | RIPK1 (0.60) | RIPK1MAPK1PTGS2 | |
| SCHEMBL10812821 | 0.84 | MAPK1 (0.74) | RIPK1MAPK1 | |
| SCHEMBL11344136 | 0.80 | KMT2A (0.56) | RIPK1MAPK1 | |
| Potassium Ion SCHEMBL11124111 | 0.80 | RIPK1 (0.47) | RIPK1MAPK1PTGS2 | |
| SCHEMBL10756564 | 0.79 | RIPK1 (0.55) | RIPK1MAPK1 | |
| SCHEMBL11353800 | 0.79 | RIPK1 (0.64) | RIPK1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060043-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC (US) | 2025-11-26 | — | — | EP | claimed |
| CN-108812681-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2021-02-26 | — | — | CN | claimed |
| EP-3174865-B1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2020-12-09 | — | — | EP | claimed |
| US-20200236925-A1 | METHODS AND FORMULATIONS FOR PREVENTING DOWNWARD MIGRATION OF AGRICULTURAL MATERIALS | DISCOVERY PURCHASER CORPORATION | 2020-07-30 | — | — | US | claimed |
| WO-2020154349-A1 | METHODS AND FORMULATIONS FOR PREVENTING DOWNWARD MIGRATION OF AGRICULTURAL MATERIALS | BAYER CROPSCIENCE LP (US) | 2020-07-30 | — | — | WO | claimed |
| US-RE48057-E1 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2020-06-23 | — | — | US | claimed |
| US-20200055846-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2020-02-20 | — | — | US | claimed |
| EP-3145312-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2019-11-20 | — | — | EP | claimed |
| EP-3160943-B1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-09-18 | — | — | EP | claimed |
| EP-3062619-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2019-07-24 | — | — | EP | claimed |
| CN-103619171-A | Pesticidal compositions and methods related thereto | DOW AGROSCIENCES LLC | 2014-03-05 | — | — | CN | claimed |
| US-20130291227-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-10-31 | — | — | US | claimed |
| US-20130288893-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-10-31 | — | — | US | claimed |
| CN-103281901-A | Pesticidal compositions and methods related thereto | DOW AGROSCIENCES LLC | 2013-09-04 | — | — | CN | claimed |
| US-20130109566-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | claimed |
| US-20130019348-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-01-17 | — | — | US | claimed |
| US-20120329649-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC | 2012-12-27 | — | — | US | claimed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | claimed |
| US-20120110701-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-03 | — | — | US | claimed |
| US-20030192070-A1 | COMPOSITION FOR HYBRID SEED PRODUCTION, PROCESS FOR THE PREPARATION OF SUCH COMPOSITION AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-10-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109566-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | PTGS2 523/4885RIPK1 2832/4885MAPK1 2599/4885 |
| US-20120110701-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, AGPS, DDT | PTGS2 553/4885RIPK1 3128/4885MAPK1 3042/4885 |
| US-20130291227-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | PTGS2 523/4885RIPK1 2832/4885MAPK1 2599/4885 |
| US-20030192070-A1 | COMPOSITION FOR HYBRID SEED PRODUCTION, PROCESS FOR THE PREPARATION OF SUCH COMPOSITION AND USE THEREOF | ZP1, KCNK4, NASP | PTGS2 4205/4885RIPK1 3482/4885MAPK1 2808/4885 |
| US-20120329649-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | PTGS2 544/4885RIPK1 2684/4885MAPK1 2628/4885 |
| US-20200055846-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | PTGS2 523/4885RIPK1 2832/4885MAPK1 2599/4885 |
| US-20130019348-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, CAT | PTGS2 1129/4885RIPK1 4144/4885MAPK1 3320/4885 |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | ACHE, DDT, PTMS | PTGS2 523/4885RIPK1 2832/4885MAPK1 2599/4885 |
| US-20130288893-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | PTGS2 523/4885RIPK1 2832/4885MAPK1 2599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.