Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | C1R | P00736 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16481863 | 0.76 | HSD11B1 (0.47) | KMOCTSKTRPA1TRPM8TRPV1 | |
| SCHEMBL8744737 | 0.73 | CTSK (0.47) | KMOSCN9ACTSKTRPA1TRPM8 | |
| SCHEMBL12066524 | 0.73 | PDE10A (0.67) | C1R | |
| SCHEMBL259080 | 0.72 | KDM4E (0.42) | CYP1A2CYP3A4 | |
| SCHEMBL21058751 | 0.70 | ACP1 (0.47) | KMOSCN9ACTSKTRPA1TRPM8 | |
| SCHEMBL20764969 | 0.70 | HSD11B1 (0.47) | KMOCTSKTRPA1TRPM8TRPV1 | |
| SCHEMBL30514768 | 0.70 | HSD11B1 (0.47) | KMOCTSKTRPA1TRPM8TRPV1 | |
| SCHEMBL4592066 | 0.69 | HSD11B1 (0.43) | KMOCTSKTRPA1TRPM8TRPV1 | |
| SCHEMBL4291142 | 0.68 | HSP90AA1 (0.64) | CTSKACP1 | |
| SCHEMBL21690275 | 0.66 | HSD11B1 (0.46) | KMOACP1CYP1A2CYP3A4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996204-A | Antidiabetic agents | PFIZER INC. (US) | 1991-02-26 | — | — | US | disclosed |