Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 3/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | C1R | P00736 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218523 | 0.78 | TRPA1 (0.40) | TRPA1 | |
| SCHEMBL8744696 | 0.76 | L3MBTL1 (0.46) | — | |
| SCHEMBL8744748 | 0.76 | IDO1 (0.41) | C1R | |
| SCHEMBL8744776 | 0.76 | LRRK2 (0.43) | ARCYP1A2CYP3A4 | |
| SCHEMBL16481863 | 0.76 | HSD11B1 (0.47) | CTSKTRPA1ARACP1KMO | |
| SCHEMBL9870039 | 0.73 | KMO (0.40) | CTSKTRPA1ACP1KMOCYP1A2 | |
| SCHEMBL7432291 | 0.72 | ADORA2A (0.41) | CTSK | |
| SCHEMBL8744699 | 0.72 | CTSS (0.61) | CTSKKMO | |
| SCHEMBL9876453 | 0.72 | ALDH1A1 (0.46) | C1R | |
| SCHEMBL8744801 | 0.71 | NUDT1 (0.38) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653421-B1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5552557-A | Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0653421-A1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |