Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105684 | 0.84 | MGLL (0.57) | HSD11B1ALDH1A1MGLL | |
| SCHEMBL6468965 | 0.83 | SRD5A2 (0.62) | HSD11B1POLBALDH1A1HTR2AHTR2C | |
| SCHEMBL6344408 | 0.83 | HSD11B1 (0.72) | HSD11B1POLBALDH1A1MGLLKDM4E | |
| SCHEMBL8149182 | 0.82 | MGLL (0.67) | HSD11B1ALDH1A1MGLL | |
| SCHEMBL662218 | 0.81 | HSD11B1 (0.64) | HSD11B1POLBALDH1A1HTR2AHTR2C | |
| SCHEMBL31164032 | 0.80 | HSD11B1 (0.68) | HSD11B1POLBALDH1A1HTR2AHTR2C | |
| SCHEMBL662115 | 0.80 | HSD11B1 (0.68) | HSD11B1POLBALDH1A1HTR2AHTR2C | |
| SCHEMBL14016112 | 0.80 | HSD11B1 (0.69) | HSD11B1POLBALDH1A1HTR2AHTR2C | |
| SCHEMBL3391936 | 0.80 | HSD11B1 (0.69) | HSD11B1POLBHTR2AHTR2CHTR7 | |
| SCHEMBL3044364 | 0.79 | HSD11B1 (0.77) | HSD11B1POLBALDH1A1MGLLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077288-A | Adrenergic, serotonin and histamine antagonist | ADIR ET COMPAGNIE (FR) | 1991-12-31 | — | — | US | disclosed |