Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498012 | 0.88 | HDAC2 (0.49) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL30169132 | 0.86 | SLC1A3 (0.46) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 | |
| Hydrochloric Acid SCHEMBL30169245 | 0.85 | SLC1A3 (0.45) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7507596 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL20581847 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL2295446 | 0.81 | FOLH1 (0.51) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL22336854 | 0.80 | ALDH1A1 (0.50) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL2300063 | 0.79 | LTA4H (0.44) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL17019229 | 0.78 | RRM1 (0.44) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL31645502 | 0.78 | RRM1 (0.44) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070139-A | PLATELET ACTIVATING FACTOR ANTAGONISTS, HYPOTENSIVES | J. URIACH & CIA. S.A. (ES) | 1991-12-03 | — | — | US | disclosed |
| US-4940706-A | 2,4-disubstituted 1,3-dioxolanes and pharmaceutical use | J. URIACH & CIA, S.A. (ES) | 1990-07-10 | — | — | US | disclosed |
| EP-0312041-A2 | 2,4-Disubstituted 1,3-dioxolanes | J. URIACH & CIA. S.A. (ES) | 1989-04-19 | — | — | EP | disclosed |