Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SCARB1 | Q8WTV0 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872568 | 0.86 | CHRNA7 (0.43) | MEN1KMT2AALDH1A1TP53CYP1A2 | |
| SCHEMBL9871319 | 0.85 | CHRNA7 (0.44) | SIGMAR1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9871678 | 0.82 | SIGMAR1 (0.44) | SIGMAR1MEN1KMT2ASCARB1ALOX15 | |
| SCHEMBL9870767 | 0.80 | MEN1 (0.34) | CDK5CDK5R1MEN1KMT2AALOX15 | |
| SCHEMBL9870860 | 0.77 | KCNH2 (0.48) | MEN1KMT2AALOX15CYP1A2CYP3A4 | |
| SCHEMBL9871424 | 0.68 | MAPT (0.40) | CDK5CDK5R1MEN1KMT2AALOX15 | |
| SCHEMBL9872690 | 0.66 | CYP3A4 (0.41) | ALDH1A1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL9870672 | 0.66 | HDAC1 (0.42) | ALDH1A1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL9872735 | 0.63 | CYP19A1 (0.41) | ALDH1A1CYP1A2CYP3A4TSHRMAPK1 | |
| SCHEMBL9873935 | 0.62 | KCNH2 (0.48) | ALDH1A1CYP1A2CYP3A4CYP2D6HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |