Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | LOX | P28300 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619236 | 0.79 | RXFP1 (0.66) | KMT2ARXFP1MEN1CA1CA2 | |
| SCHEMBL8878223 | 0.78 | ALDH1A1 (0.55) | KMT2ARXFP1MEN1CA1CA2 | |
| SCHEMBL20679850 | 0.75 | ALDH1A1 (0.45) | KMT2ARXFP1MEN1CA1CA2 | |
| SCHEMBL11722903 | 0.75 | RXFP1 (0.47) | KMT2ARXFP1MEN1CA1CA2 | |
| SCHEMBL9870456 | 0.74 | RECQL (0.41) | KMT2ARXFP1MEN1CA1CA2 | |
| SCHEMBL9871974 | 0.74 | RXFP1 (0.51) | KMT2ARXFP1MEN1CA1CA2 | |
| SCHEMBL5299686 | 0.72 | ADORA3 (0.46) | CA1CA2LOXLOXL2ALDH1A1 | |
| SCHEMBL7513501 | 0.72 | ADORA3 (0.46) | KMT2AMEN1CA1CA2LOX | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.72 | TSHR (0.68) | KMT2ACA1CA2LOXLOXL2 | |
| Benzylsulfonylbenzene SCHEMBL1877584 | 0.70 | TSHR (0.66) | KMT2ACA1CA2LOXLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992456-A | Plant protection | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | claimed |
| EP-0369234-A2 | 2,5-Disubstituted 1,3,4-thiadiazole derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1990-05-23 | — | — | EP | claimed |
| US-4992456-A | Plant protection | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4992456-A | Plant protection | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0369234-A3 | 2,5-DISUBSTITUTED 1,3,4-THIADIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| EP-0369234-A2 | 2,5-Disubstituted 1,3,4-thiadiazole derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0369234-A2 | 2,5-Disubstituted 1,3,4-thiadiazole derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1990-05-23 | — | — | EP | disclosed |